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Results for Search : "507 Education, research & related topics"
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Situational analysis on family planning and reproductive health education in Malaysia and other selected Muslim countries Part I: needs analysis on family planning policy Part II: reproductive health education: policy and plan of action
Item Type: Research Report
Author: 
National Population and Family Development Board, Malaysia,  and
Author: 
Editor: 
Year:  00/00/2020
Abstract:  This study is an initiative by the Ministry of Women, Family and Community Development (MWFCD) through the National Population and Family Development Board (NPFDB) in collaboration with the United Nations Population Fund (UNFPA), who has been a strategic partner of NPFDB since the 1990s in the Sexual and Reproductive Health (SRH) programmes. This study was conducted at where there are rapid changes in the population dynamics and demographic trends together with the advancement in human capacity development and new communication technologies. It is an effort that enables the nation to achieve its commitment locally towards Malaysia’s Shared Prosperity Vision 2030 agenda and internationally, such as the ICPD Plan of Action. The objective of the study is to identify the best practices of reproductive and sexual health (SRH) programs including family planning and reproductive and sexual health education (SRHE) among selected Islamic countries that practice sunni sects to provide direction to Malaysia. Five (5) countries were selected for the purpose of comparison with Malaysia are Turkey, Egypt, Morocco and Bangladesh. The report of this study proposes several strategies and improvements as a result of a gap analysis with other Muslim countries that can help strengthen the strategy and implementation of the National Sexual and Reproductive Health programmes to improve reproductive health indicators such as Maternal Mortality Rate, Infant Mortality Rate and Age Specific Fertility Rate, as well as reducing the number of cases of teenage pregnancy, abortion, sexual abuse and sexual crimes.
 
 
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Kajian Pengesanan Mikrodelesi Kromosom Y dalam kalangan klien Infertiliti di Lembaga Penduduk dan Pembangunan Keluarga Negara
Item Type: Research Report
Author: 
Lembaga Penduduk dan Pembangunan Keluarga Negara, Malaysia,  and
Author: 
Editor: 
Year:  02/01/2017
Abstract:  The study "Microdelesi of Y Chromosome among NPFDB Infertility Clients" conducted by the Biomedical Unit, NFPDB is to identify infertility factors from a genetic aspect. Study samples were obtained from infertility patients referred to the Cytogenetic Laboratory, NPFDB from 2003 to 2010. A total of 100 blood samples of clients diagnosed as azoospermia (48), severe oligoasthenoteratozoospermia (24), oligozoospermia (15), severe oligozoospermia (6), Klinefelter Syndrome (3) and idiopathy (4) were performed Chromosome Analysis Tests to identify any abnormalities of the number and structure on the chromosome and subsequently Molecular Testing is performed to detect the microdeletion of the Y chromosome. Majority of ethnic groups involved in the study are Malays, which is 74 people (74%) followed by Chinese; nine (9) people (9%), Indians; seven (7) people (7%) and other ethnicities from Sabah and Sarawak as many as 10 people (10%) in the age range of 23 to 46 years.The chromosome analysis test results for the 100 samples were normal which is, 46, XY, no abnormalities in the structure or number of chromosomes were found. Results was found that 15 samples (15%) underwent Y chromosome microdeletion at the AZF locus in molecular test. From 15 samples, 10 samples were azoospermia, three (3) severe oligoasthenoteratozoospermia samples and two (2) oligozoospermia samples. Each sample experienced deletion at different locus and there were samples that experienced multiple deletion which involved deletion of more than one factor locus (AZF).The most common AZF factors found to experience deletion were AZFc (73.33%) followed by AZFb (53.33%), AZFd (40%) and AZFa (13.33%). In conclusion, it was found that genetic factors are one of the causes of infertility problems among clients came for subfertility treatment. Looking at the importance of undergoing genetic screening testing at an early stage, it is recommended that this test be tested for men diagnosed with azoospermia and severe oligozoospermia at the Subfertility Clinic, NPFDB. The information obtained has prognostic value and influences the medical therapy chosen to assist in the clinical management of the client and his descendant in the future.
 
 
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Kajian perbandingan penggunaan tiga jenis rawatan hormon FSH dalam kalangan pesakit subfertiliti yang menjalani prosedur permanian beradas di Lembaga Penduduk dan Pembangunan Keluarga Negara
Item Type: Research Report
Author: 
Lembaga Penduduk dan Pembangunan Keluarga Negara, Malaysia,  and
Author: 
Editor: 
Year:  02/01/2017
Abstract:  Since 1979, the National Population and Family Development Board (NPFDB) has been providing subfertility management services to the public especially middle-income group. In line with the rapid pace of the latest technology and research developments, there are various types of fertility drugs in the form of injections which had been used in subfertility treatment. The main function of this injection is to mature the follicles where the main hormone contained in this injection is the follicle stimulating hormone (Follicle Stimulating Hormone, FSH). In general, there are three types of FSH injections, which is a recombinant FSH (rFSH) that have 100 percent synthetic hormone, urinary FSH (uFSH) that derived from menopausal urine and highly purified urinary FSH (hp-uFSH) that also derived from menopausal urine but more pure state than uFSH. All three hormones have FSH’s activities but uFSH and hp-uFSH also have Luteinizing Hormone’s activity (LH). Thus, NPFDB has taken initiative to conduct a comparative study on the use of three types of FSH hormone treatment, namely Gonal F (rFSH), Folliova (uFSH) and Menopur (hp-uFSH), among subfertilitie’s patient who’s undergoing Intrauterine Insemination Technique (IUI). Among others, the three types of hormones were studied in terms of effevtivenee and cost burden. The study sample was from patients with unknown cause of subfertilitie’s problem and they visit NPFDB Subfertilitie’s Clinic, Headquarters, from June 2010 to May 2012. The sampling method was random. The patient and researcher do not know the treatment regimen to be initiated until a closed sample containing the treatment regimen code number is opened by the patient before starting treatment. Data were collected, recorded and anlyzed using Statistical Package for the Social Sciences (SPSS) software. Although originally a total of 90 female patients were targeted to be recruited into this study. 30 patients for each type of FSH hormone, but at the end of the study only 39 patients met all eligibility criteria and agreed to participate in this study. The result showed that average of the patients was 28.3 years and the majority were ethnic Malays (76.9%). Most of the patients had a household income between RM 5,000.00 and RM 10,000.00 (51.4%). The percentage of patients requiring more than three injections to procedure mature follicles was lowest for Folliova (41.7%), compared with Menopur (50.0%) and Gonal F (55.6%). Similarly in terms of the number of follicles produced, the Folliova regime (58.3%) produced more follicles (more than three follicles) than other regimes. A total of 16.7 percent of patients who took Menopur injections were confirmed pregnant, while no pregnany occurred among patients who took Folliova and Gonal F. In terms of cost, at the time of this study, the price of three 75IU injections was RM 334.20 for Gonal F, RM 187.20 for Folliova and RM 271.20 for Menopur. In conclusion, this study shows that, hp-uFSH (Menopur) gives the highest pregnancy rate compared to Gonal F and Folliova. Furthemore, the price of Menopur is moderate (affordable) for patients. Therefore, highly purified urinary FSH is a good gonadotropin choice for couples with unexplained subfertility undergoing an IUI procedure and it may be the main choice for patients who need a combination fertility pill stimulation regimen and gonadotropin injections. As a suggestion, such a study should be conducted with a larger sample size to obtain more significant results and be representative of actual population.
 
 
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