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Maternal reciprocal translocation t(1p;6p) in a couple with recurrent spontaneous abortion


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Item type Article
Subjects 600 Technology > 610 Medicine & health > 618 Gynecology, obstetrics, pediatrics & geriatrics
Division/Agency LPPKN - National Population and Family Development Board, Malaysia: Human Reproductive Division
Keywords Reciprocal translocation, Chromosomal abnormalities, Spontaneous abortion
Additional Information The hard copy can be refer at Resource Centre, NPFDB.
Abstract G-banded chromosome complements were analyzed from peripheral blood lymphocytes of a couple who had experinced for spontaneous abortions. The karyotype of the husband was designated as 46,XY, while the wife's karyotype was designated as 46,XX, t(1p;6p). Balanced reciprocal translocations appear to be associated with the recurrent spontaneous abortions experienced by the couple. We report here a case of a maternal (1p;6p) reciprocal translocation in a couple with repeated fetal loss.
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