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Effect of norgestrel and testosterone on male rats


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Item type Article
Subjects 600 Technology > 610 Medicine & health > 618 Gynecology, obstetrics, pediatrics & geriatrics
Division/Agency LPPKN - National Population and Family Development Board, Malaysia: Human Reproductive Division
Keywords Male contraceptive, Libido, Spermatogenesis
Additional Information The hard copy can be refer at Resource Center, NPFDB.
Abstract Intramuscular administration of Norgestrel, an orally active progestogen, to male rats for 48 days interrupted spermatogenesis and also caused a temporary loss of libido. Testosterone therapy restored libido in progesterone treated rats but not the spermatogenic process. Consequent upon these findings, a new combination of Norgestrel and Testosterone, capable of inducing temporary sterility in male rats, has been evolved.
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