| Item type |
Conference or Workshop Item |
| Subjects |
600 Technology > 610 Medicine & health |
| Division/Agency |
LPPKN - National Population and Family Development Board, Malaysia: Population and Family Research Division |
| Keywords |
Infertility, Intra uterine insemination (IUI), Prognostic factors, Clomiphene citrate, Human menopausal gonadotrophin (HMG) |
| Additional Information |
Author from Faculty of Medicine, University Malaya. |
| Abstract |
The purpose of the study was to determine prognostic factors that affect the success rate of Intrauterine Insemination (IUI) as well as association of prognostic factors with success rate of IUI treatment for infertile couples. A retrospective cohort study investigating the prognostic factors affecting success of IUI was done at National Infertility clinic. A total of 1585 couples involving 3249 IUI cycles with ovarian stimulation using clomiphene citrate and/or human menopausal gonadotrophin (HMG) were recruited from lst January 2000 till 3lst December 2006. The pregnancy rate per cycle and per couple was 3.7% and 7.4%, respectively. Logistic regression analysis had determined three prognostic variables as regards pregnancy namely as duration of infertility a = 0.002), interval of menstrual cycle a = 0.00025) and sperm count a = 0.016). The percentage of women successfully pregnant after cycle one till cycle 5 IUI were ranging from 3.4% to 4.8%. Results showed that no pregnancy occurred after the sixth cycle of IUI. The result suggests that duration of infertility is of utmost important determinants of an infertile couple in view of IUI success rate. |
