| Item type |
Article |
| Subjects |
600 Technology > 610 Medicine & health > 618 Gynecology, obstetrics, pediatrics & geriatrics |
| Division/Agency |
LPPKN - National Population and Family Development Board, Malaysia: Human Reproductive Division |
| Keywords |
Early embryonic development, Endogenous hormones, Lipid constituents |
| Additional Information |
The hard copy can be refer at Resource Centre, NPFDB. |
| Abstract |
Effect of Centchroman (3,4-trans-2, 2-dimenthyl-3-phenyl-4-p (B-pyrrolidinoethoxy)-phenyl-7-methoxy chroman)treatment at 1 and 2.5 mg/kg; for 3, 6 and 12 months on lipids constituents of uterus,cervix and vagina was studied. Centchroman did not cause any consistent pattern of alteration in lipid contents of uterus, cervix and vagina of female rhesus monkey. However, uterine phospholipids were decreased at both the doses and cervical and vaginal triglycerides increases at higher dose. The altered nature of responses in the genital organs may be due to manifestation of estrogenic-cum-antiestrogenic properties of centchroman. |
