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Effect of norgestrel and testosterone on male rats
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Item type | Article |
Subjects | 600 Technology > 610 Medicine & health > 618 Gynecology, obstetrics, pediatrics & geriatrics |
Division/Agency | LPPKN - National Population and Family Development Board, Malaysia: Human Reproductive Division |
Keywords | Male contraceptive, Libido, Spermatogenesis |
Additional Information | The hard copy can be refer at Resource Center, NPFDB. |
Abstract | Intramuscular administration of Norgestrel, an orally active progestogen, to male rats for 48 days interrupted spermatogenesis and also caused a temporary loss of libido. Testosterone therapy restored libido in progesterone treated rats but not the spermatogenic process. Consequent upon these findings, a new combination of Norgestrel and Testosterone, capable of inducing temporary sterility in male rats, has been evolved. |