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Results for Item type : "Article"
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Hemorrheology and fibrinolytic response in women taking oral contraceptive pills
Item Type: Article
Editor:
Year: 00/12/1987
Abstract: A study was conducted on a total of 107 women attending the National Population and Family Development Board, Malaysia (NPFDB) Maternity Hospital, Kuala Lumpur. The subjects were divided into 3 groups. Group I and II consisted of woman on a low-dose combined estrogen and progestagen pills for a duration of 3-6 months and 1-2 year respectively. Group III was a control group consisting of women not on pills. A series of tests to evaluate hemorrheology and the fibrinolytic response were carried out. The results obtained showed no definite or significant difference in the two systems for all the three groups investigated. These findings are comparable to those reported by other investigators, implying relative safety of these pills in the local population.
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A five-year review of diagnostic laparoscopy and female sterilizations in 52 centers in Malaysia
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Doctors participating in the Laparoscopy Program of the National Population and Family Development Board, Malaysia return data on all cases of diagnostic laparoscopy and female sterilizations carried in their centres. Data on 2,179 cases of diagnostic laparoscopy and 4,740 cases of female sterilizations for the period 1981-1985 are analysed. States with the highest return rates are Kuala Lumpur Federal Territory, Negeri Sembilan, Johor and Perak. The Specialist Centre of the Board alone accounted for one-third of the cases. Data for female sterilizations are further analysed. Complication rates for laparoscopy and minilaparotomy techniques are low at between 0.5 to 2.5 per 100 procedures. All doctors providing such services should be encouraged to participate in this Program and submit data in order to improve and learn from this Program.
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In vitro maturation of immature human oocytes in culture medium containing follicular fluid
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: In clinical IVF programs often immature oocytes are retrieved. Under such circumstances, numerous workers have advocated the procedure of pre-incubation in insemination medium for 12-36 hours, prior to insemination to induce maturation. We describe here the supplementation of follicular fluid in insemination medium to induce maturation of immature oocytes. The culture characteristics of the insemination medium containing follicular fluid appears to be better than the insemination medium without follicular fluid. Previous reports suggest the presence of a meiosis-inducing substance in follicular fluid which could trigger the resumption of meiosis and hence contribute to oocyte maturation. Other factors in follicular fluids which are yet to be elucidated, may also contribute to oocyte maturation. It is concluded that superior culture characteristics can be obtained if immature oocytes are preincubated for 16-36 hours in insemination medium containing 50% follicular fluid.
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Maternal reciprocal translocation t(1p;6p) in a couple with recurrent spontaneous abortion
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: G-banded chromosome complements were analyzed from peripheral blood lymphocytes of a couple who had experinced for spontaneous abortions. The karyotype of the husband was designated as 46,XY, while the wife's karyotype was designated as 46,XX, t(1p;6p). Balanced reciprocal translocations appear to be associated with the recurrent spontaneous abortions experienced by the couple. We report here a case of a maternal (1p;6p) reciprocal translocation in a couple with repeated fetal loss.
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Paramedic insertion of intrauterine device in a Malaysian family planning clinic
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: A retrospective study was carried out in a Malaysian urban family planning clinic to evaluate the effectiveness of the paramedic in intrauterine contraceptive device (IUD)insertion. Seventy-nine multiload Cu 250 insertions by trained senior nurse in 1983 were measured against 369 insertions by doctors. Follow-up was done by nurses. At the cut-off date on 31st October 1985, the case records were examined. It was found that there was no statistically significant difference in termination percentage due to IUD complications. The nurse's group had a significantly higher percentage of failure to follow-up and also removal for personal reasons. No significant difference between the 2 groups was shown for termination due to accidental pregnancy, bleeding and pain, expulsion and pelvic infections. Removal of IUD to plan for pregnancy is high in both groups. The results show that the trained paramedic can be just as effective as doctors for IUD insertion.
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Effect of centchroman on lipid metabolism in genital organs of female rhesus monkeys (macaca mulatta)
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Effect of Centchroman (3,4-trans-2, 2-dimenthyl-3-phenyl-4-p (B-pyrrolidinoethoxy)-phenyl-7-methoxy chroman)treatment at 1 and 2.5 mg/kg; for 3, 6 and 12 months on lipids constituents of uterus,cervix and vagina was studied. Centchroman did not cause any consistent pattern of alteration in lipid contents of uterus, cervix and vagina of female rhesus monkey. However, uterine phospholipids were decreased at both the doses and cervical and vaginal triglycerides increases at higher dose. The altered nature of responses in the genital organs may be due to manifestation of estrogenic-cum-antiestrogenic properties of centchroman.
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A prospective study of the acceptability of today vaginal contraceptive sponge among Malaysian women
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Fifty volunteers were selected in a two month prospective study to evaluate the acceptability of the Today vaginal sponge contraceptive among Malaysian women. One participant developed allergic reaction to the sponge and was taken off at an early stage of the study. Fourty- nine participants completed one month follow-up.Thirteen subjects discontinued for various reasons which are related and not related to the sponge. The remaining 36 participants completed the study. Few side effects were observed among the sponge users who completed the trial. One subject complained that the Loop of the sponge hurt her husband's penis. Most of the women who are on the sponges claimed that sexual intercourse is no longer messy. Four subjects claimed that the sponges pontentiated sexual feeling to their male partners. The sponge is generally accepted by the study group, which suggest that the general impression 'Asian Women abhor any form of vaginal contraception' is not totally correct. It is suggested that the contraceptive efficacy of the sponge be evaluated among our women in the future.
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Effect of norgestrel and testosterone on male rats
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Intramuscular administration of Norgestrel, an orally active progestogen, to male rats for 48 days interrupted spermatogenesis and also caused a temporary loss of libido. Testosterone therapy restored libido in progesterone treated rats but not the spermatogenic process. Consequent upon these findings, a new combination of Norgestrel and Testosterone, capable of inducing temporary sterility in male rats, has been evolved.
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Apparent benefit from corticosteroids in bronchopulmonary dysplasia: a case report
Item Type: Article
Editor:
Year: 00/00/1984
Abstract: A case of bronchopulmonary dysplasia complicating the ventilatory management of respiratory distress syndrome is described. The diagnosis was documented by typical clinical radiological and cytopathologic criteria. The infant's abrupt clinical deterioration was reversed by the use of high dosage steroids and attempt at reducing the dose of steroids initially was associated with clinical and radiological deterioration. We conclude that steroid administration seemed beneficial in our patient.
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Age of biological maturity of Malaysian girls by ethnicity
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: This study tries to estimate the age of biological maturity of Malaysian girls by ethnicity by employing an indirect methodology. Age at biological maturity is estimated by considering retrospective fertility and family survey data on marriage, first birth, and contraceptive use. The waiting time for the biological mature females to conceive is 3.0 months; 3.2 months among the Malays, 2.7 months among the Chinese, and 2.8 months among the Indians.The maximum age of attaining biological maturity is 20 for all ethnic groups except Indians (19 years). The expected age biological maturity at birth is 15.6 years; 15.3 years for the Malays, 15.4 for the Chinese and 14.8 years for the Indians.The mean age of attaining biological maturity coincides with the expected age of attaining biological maturity at birth.
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