TOPICS
Results for Topics : "Fertility"
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Isu kesuburan: cabaran global, tanggungjawab bersama
Item Type: Conference or Workshop Item
Editor:
Year: 00/07/2025
Abstract: Malaysia is expected to reach an aging society status by the year 2035, in line with the trend of declining total fertility rate (TFR) of the country, which is currently below the replacement level of 2.1 children per woman. The state of Kedah also reflects the same pattern, registering a TFR of around 1.7 to 1.8 according to DOSM data (2022). This decline has significant implications for the future workforce, social support systems, and the state's economic stability, especially in facing the challenges of an aging population and a long-term decrease in population growth rate.
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Obesity, subfertility and fetal programming: a vicious cycle
Item Type: Conference or Workshop Item
Editor:
Year: 00/07/2025
Abstract: Obesity increasing rapidly, especially among reproductive age women. Obesity affects fertility, pregnancy outcomes, and future generations. Obesity disrupts reproductive hormones and leads to anovulation, PCOS, poor oocyte quality. Maternal obesity leads to pregnancy complications. Fetus exposed to hyperglycemia and oxidative stress.
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Trend fertiliti di Pahang: implikasi terhadap pembangunan ekonomi dan sosial di Pahang
Item Type: Conference or Workshop Item
Editor:
Year: 00/07/2025
Abstract: Although there is a decline in fertility rates and population growth in Pahang, macroeconomic indicators such as GDP growth rate, unemployment rate, and direct investment still show stable performance. This demographic effect is slow but certain, and will have a profound impact in the medium and long term. Early signs may not be noticeable in macro figures, but long-term risks have already begun to appear.
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Laporan Seminar Kependudukan Negeri Sembilan Sempena Hari Penduduk Sedunia 2025
Item Type: Report
Editor:
Year: 00/07/2025
Abstract: In conjunction with the celebration of World Population Day 2025 at the Negeri Sembilan level, the Negeri Sembilan state of National Population and Family Development Board (LPPKN) in collaboration with the Department of Statistics Malaysia Negeri Sembilan, Universiti Sains Islam Malaysia, Negeri Sembilan Economic Planning Unit, KPJ Healthcare University and Universiti Teknologi MARA Negeri Sembilan organized the Negeri Sembilan Population Seminar at the Universiti Sains Islam Malaysia, Negeri Sembilan on 24 July 2025. The theme of the Negeri Sembilan World Population Day celebration this time is "Fertility and Economic Competitiveness: Understanding the Impact on the Labor Market". Also held at this celebration was the Population Forum entitled "Fertility and Economic Competitiveness: Understanding the Impact on the Labor Market". Three (3) working paper presentations were also presented, namely demographic issues, reproductive health and fertility.
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Penemuan Utama Tinjauan Pendapat Umum Bersempena Sambutan Pendapat Umum Bulan Kesedaran Kanser Serviks 2025
Item Type: Infographic
Editor:
Year: 00/06/2025
Abstract: In conjunction with the 2025 Cervical Cancer Awareness Month, the
Ministry of Women, Family and Community Development (KPWKM),
through the National Population and Family Development Board
(LPPKN), conducted an online public opinion survey to assess the
knowledge, attitudes, and practices (KAP) of women in Malaysia
regarding cervical cancer. The survey was carried out from 23
January to 17 February 2025. A total of 3,050 respondents, Malaysian
women aged 18 and above, participated in the survey.
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Podcast Kasih Lensa Keluarga: Jejak Subfertiliti – Sejarah, Stigma & Harapan
Item Type: Video
Editor:
Year: 23/04/2025
Abstract: This episode highlights the distinguished contribution of Dato’ Dr. Hamid Arshat, Consultant Obstetrician and Gynaecologist (OBGYN), a renowned medical pioneer who has led the development of subfertility treatment in Malaysia for more than four decades. He will share his personal journey, challenges encountered, and key achievements in advancing fertility care in the country. The session also features Dr. Halimatul Saadiah Mohd Aris, Deputy Director of the National Subfertility Specialist Centre, LPPKN.
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Podcast KASIH Lensa Keluarga: IUI, TI, IVF @ ICSI - Mana yang sesuai?
Item Type: Video
Editor:
Year: 24/03/2025
Abstract: This session of the KASIH Lensa Keluarga Podcast explores key fertility treatment options, namely Intrauterine Insemination (IUI), Timed Intercourse (TI), In Vitro Fertilisation (IVF), and Intracytoplasmic Sperm Injection (ICSI). The discussion features Dr. Lee Yeh Han, Senior Assistant Director, Subfertility Unit, LPPKN, and Dr. Adilah Ahmat, Consultant Obstetrician and Gynaecologist, LPPKN Fertility Clinic (FPP). The panel will provide detailed insights into the procedures, effectiveness, and suitability of each method based on individual needs. This session aims to enhance public understanding of available fertility treatments in Malaysia and to promote greater awareness of reproductive health.
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Dapatan data subfertitli Kebangsaan bagi tahun 2023
Item Type: Infographic
Editor:
Year: 00/12/2024
Abstract: The collection of subfertility data involves all registered hospitals and clinics providing subfertility treatment services throughout Malaysia from January 1, 2023, to December 31, 2023. The collected subfertility data has been approved by NPFDB (LPPKN), including information on the profiles of new female and male clients (husbands) in the current year, as well as details of subfertility treatments carried out at the participating facilities during the same period.
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Exploring environmental contaminants and dietary pattern in relation to infertility in reproductive age women
Item Type: Scientific Poster
Editor:
Year: 00/11/2024
Abstract: Identifying modifiable lifestyle factors, such as diet, that influence human fertility is of major clinical and public health significance. Medical treatment for impaired fecundity is also on the rise. The use of assisted reproductive technologies in Malaysia has steadily increased. This study aims to explore environmental contaminants and dietary pattern in Malaysian reproductive age women. This case control study will involve cross-sectional analysis of 128 women with infertility, with matched 256 regular cycling women from a community-based cohort. Sociodemographic data, mental health, physical activity and dietary intake for 7 days were obtained from interviews using questionnaires. Anthropometric measurements including weight, height, BMI, and body fat percentage were collected. Physical activity data showed that infertile women have lower physical activity compared to those in control and higher stress and depression. Data analysis using multivariate tests showed that an increase in one unit of BMI increased the risk of infertility in women by 1.15 times [Adjusted OR=1.147 (95% CI= 1.059-1.243)])(p<0.01).Meanwhile, high intake of folic acid will reduce the risk of infertility in women by1.0% [Adjusted OR=0.990 (95% CI= 0.981-1.000)] (p<0.05). Likewise, highselenium intake also reduced the risk of infertility in women by 3.0% [Adjusted OR=0.972 (95% CI= 0.949-0.996)] (p<0.05). Significant differences were observed in Anti Mullerian Hormone levels, FSH, LH, lipid peroxidation, advanced glycation end products, inflammatory markers, micronucleus frequency (chromosomal damage), insulin (HOMA-IR), fasting insulin, lipid profile and fasting blood glucose. Based on the hair heavy metal analysis, it was observed that zinc, selenium, calcium and chromium is lower in case group as compared to the control group. On the other hand, lead, copper and cadmium were observed to be higher in case as compared to control. It was observed that urinary bisphenol A and Phtalate metabolites are higher in case group. Di-(2-ethylhexyl) phthalate (DHEP), MEHHP, Mono (2-ethyl-5-hydroxyhexyl) phthalate and MEOHP, mono (2-ethyl-5-oxohexyl) phthalate are detected in our case group. For paraben, only methyl paraben were higher in the cases but not other paraben metabolites. Per- and polyfluorinated substances) concentration observed is not significant. Based on the metabolomic analysis, the pathway with the highest impact factor was the synthesis and degradation of ketone bodies, with an impact factor of 0.60. This indicates that this pathway is very important in the metabolic network and has a significant impact on the overall system. Other pathways with high impact factors include Phenylalanine, tyrosine and tryptophan biosynthesis (0.5), Taurine and hypotaurine metabolism (0.42), Phenylalanine metabolism (0.35), Histidine metabolism (0.32), Cysteine and methionine metabolism (0.274), Glycine, serine and threonine metabolism (0.271), and glyoxylate and dicarboxylate metabolism (0.21). Based on our findings, risk factors which include BMI, intake of folic acid and selenium have a significant relationship with the risk of infertility in women. We have also shown that there is existence of endocrine disrupting chemicals affecting infertility but the cause or the source of contamination is still unknown. Pathway related to ketone bodies and tricarboxylic acid is involved showing the relationship with healthier weight for better reproductive outcome. We have also showed that higher genomic instability and inflammation was observed in those infertile showing that managing dietary and lifestyle related to it is very crucial. Therefore, healthy lifestyle practices need to be improved, targeted and personalized to reduce the risk of infertility in women.
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Meneroka kontaminan persekitaran dan corak diet dalam kalangan wanita umur reproduktif yang mengalami ketidaksuburan
Item Type: Conference or Workshop Item
Editor:
Year: 00/11/2024
Abstract: The environment and dietary patterns have a significant impact on reproductive-age women experiencing infertility. Every year, fertility rates among women decline in many countries. Pollutants are constantly present in our surroundings, and environmental contaminants are commonly found in food, cooking ingredients, medications, and kitchenware that we use daily, which contribute to the causes of female infertility. Therefore, there is a need for monitoring the food industry/chemicals in food and raising public awareness about the importance of being mindful of both their diet and the surrounding environment.
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