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Effect of centchroman on lipid metabolism in genital organs of female rhesus monkeys (macaca mulatta)
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Effect of Centchroman (3,4-trans-2, 2-dimenthyl-3-phenyl-4-p (B-pyrrolidinoethoxy)-phenyl-7-methoxy chroman)treatment at 1 and 2.5 mg/kg; for 3, 6 and 12 months on lipids constituents of uterus,cervix and vagina was studied. Centchroman did not cause any consistent pattern of alteration in lipid contents of uterus, cervix and vagina of female rhesus monkey. However, uterine phospholipids were decreased at both the doses and cervical and vaginal triglycerides increases at higher dose. The altered nature of responses in the genital organs may be due to manifestation of estrogenic-cum-antiestrogenic properties of centchroman.
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A prospective study of the acceptability of today vaginal contraceptive sponge among Malaysian women
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Fifty volunteers were selected in a two month prospective study to evaluate the acceptability of the Today vaginal sponge contraceptive among Malaysian women. One participant developed allergic reaction to the sponge and was taken off at an early stage of the study. Fourty- nine participants completed one month follow-up.Thirteen subjects discontinued for various reasons which are related and not related to the sponge. The remaining 36 participants completed the study. Few side effects were observed among the sponge users who completed the trial. One subject complained that the Loop of the sponge hurt her husband's penis. Most of the women who are on the sponges claimed that sexual intercourse is no longer messy. Four subjects claimed that the sponges pontentiated sexual feeling to their male partners. The sponge is generally accepted by the study group, which suggest that the general impression 'Asian Women abhor any form of vaginal contraception' is not totally correct. It is suggested that the contraceptive efficacy of the sponge be evaluated among our women in the future.
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Effect of norgestrel and testosterone on male rats
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Intramuscular administration of Norgestrel, an orally active progestogen, to male rats for 48 days interrupted spermatogenesis and also caused a temporary loss of libido. Testosterone therapy restored libido in progesterone treated rats but not the spermatogenic process. Consequent upon these findings, a new combination of Norgestrel and Testosterone, capable of inducing temporary sterility in male rats, has been evolved.
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Apparent benefit from corticosteroids in bronchopulmonary dysplasia: a case report
Item Type: Article
Editor:
Year: 00/00/1984
Abstract: A case of bronchopulmonary dysplasia complicating the ventilatory management of respiratory distress syndrome is described. The diagnosis was documented by typical clinical radiological and cytopathologic criteria. The infant's abrupt clinical deterioration was reversed by the use of high dosage steroids and attempt at reducing the dose of steroids initially was associated with clinical and radiological deterioration. We conclude that steroid administration seemed beneficial in our patient.
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Age of biological maturity of Malaysian girls by ethnicity
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: This study tries to estimate the age of biological maturity of Malaysian girls by ethnicity by employing an indirect methodology. Age at biological maturity is estimated by considering retrospective fertility and family survey data on marriage, first birth, and contraceptive use. The waiting time for the biological mature females to conceive is 3.0 months; 3.2 months among the Malays, 2.7 months among the Chinese, and 2.8 months among the Indians.The maximum age of attaining biological maturity is 20 for all ethnic groups except Indians (19 years). The expected age biological maturity at birth is 15.6 years; 15.3 years for the Malays, 15.4 for the Chinese and 14.8 years for the Indians.The mean age of attaining biological maturity coincides with the expected age of attaining biological maturity at birth.
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Determinants of neonatal outcome in a Malaysian Maternity Hospital, 1980-1981
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: The compilation and analysis of basic perinatal statistics in the Maternity Hospital, Kuala Lumpur is described. The study period covers the years 1980-1981. Determinants of neonatal mortality include very low birthweight (<1.5 kg), a gestational age of less than 32 weeks and clinical conditions of asphyxia, bacterial sepsis and respiratory distress syndrome. A proposal for a clinical classification of neonatal mortality is advanced and implications for a wider applicability of this approach is suggested to better evaluate perinatal performance in hospitals all over the country.
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The pattern of maternal mortality at Maternity Hospital Kuala Lumpur
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: From 1978 to 1981, there were 70,000 deliveries at Maternity Hospital, Kuala Lumpur. 39 maternal mortalities were encountered during this four year period. The major causes of death were toxemia, hemorrhage, embolism, medical disease in pregnancy, sepsis, uterine inversion, obstetric trauma, Mendelson and pulmonary edema. Avoidable factors were isolated in all the mortalities except in three, one due to infective hepatitis and two due to cardiac disease in pregnancy. The patient was at fault in four mortalities. The need for documenting all maternal mortalities is a priority in this country to make analysis more meaningful.
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Office laparoscopic assessment of female fertility
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: The preliminary report details our experience and also serves to evaluate the risk benefits of office laparoscopy for female fertility assessment in 183 subjects. The patients were admitted at about 8.00 in the morning and discharged at 3.00 to 4.00 in the afternoon after laparoscopy has been performed. Only 7.7 percent of the subjects required inhalational anesthetic gases along with a combination of intravenous sedation and local anesthetic infiltration. The pick-up rate for pelvic abnormality is fairly high, approximately 22.4 percent. Difficulties and complications encountered during laparoscopy were minimal and easily overcome.The benefits of laparoscopy overrules assessment and sterilization feature laparoscopy on an 'outpatient basis' as one of its main activities.
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Actinomyces-like organisms in the cervical smears of IUCD users
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: Cervical smears of 128 intrauterine contraceptive device users were stained by Gram stain and screened for the presence of Actinomyces-like organisms. Actinomyces-like organisms were observed in 5.5 percent, pus cell in 20.1 percent and yeast cells in 10.2 percent of the smears examined. The average duration of insertion was 8 months. Smears of 103 controls were negative for Actinomyces-like organisms, pus cells were observed in 8.7 percent and yeasts in 4.8 percent.
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Problems of neonatal surgery in Malaysia
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: From January 1970 to May 1981, there were 594 neonates admitted to the General Hospital, Kuala Lumpur for surgery. Three hundred and seventy-one cases bad major alimentary tract alimentary tract abnormalities 97.1 percent of which caused obstruction. High gut anomalies and diaphragmmatic hernia (Group A cases) were relatively uncommon and the overall post-operative mortality for this group was high (64.6 percent). Overall mortality declined from 75.0 percent in 1970 to 10.3 percent for the first six month of 1981. Death rate among the low birth weight infants and those with multiple anomalies however, remain high. Factors related to post-operative mortality are discussed. Foremost among them is the time of referral to the surgeon. Various problems of management in this hospital are also highlighted.
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