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Effects of friends feminine wipes on sperm viability in-vitro
Item Type: Article
Editor:
Year: 00/12/1990
Abstract: Friend feminine wipes, disinfectant impregnanted fibre tissues meant for the maintenance of female hygiene, was evaluated for its effect on sperm viability in-vitro and found to be spermicidal. These feminine wipes are therefore not recommended for use at coitus in couples who are planning pregnancies. Although the wipes were found to have spermicidal properties they are not recommended for the purpose of contraception.
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Clinical evaluation of Buserelin, a GnRH analogue in the management of moderate to severe pelvic endometriosis
Item Type: Article
Editor:
Year: 00/12/1990
Abstract: A local study, a part of a multinasional and multicenter study on the efficacy and safety of Buserelin was carried out for the treatment of pelvic endometriosis using a standard protocol. 20 women diagnosed to have moderate to severe endometriosis by laparoscopy were recruited. The women were given 900 micrograms Buserelin acetate daily by intranasal spray for a fixed period of 6 months. Baseline hormonal and biochemical parameters were taken prior to treatment and the parameters were repeated during each follow-up at weekly and monthly intervals. In addition, changes in symptoms were monitored. A second look laparoscopy was performed at completion of therapy and patients were followed up for a further 6 months. There was 100 percent suppression of oestradiol levels during the 6 months treatment period. An improvement of implants according to AFS classification occured in all patients. One patient discontinued because of side effects. Restoration of cycles after completion of therapy occured within 7 weeks. There were 7 pregnancies (64%) in the first 6 months after treatment for those wanting pregnancies. During therapy, dysmenorrhoea, pelvic pain and dyspareunia improved considerably. Buserelin was proven to be effective in the management of pelvic endometriosis and is well tolerated and safe.
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Maternal reciprocal translocation t(1p;6p) in a couple with recurrent spontaneous abortion
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: G-banded chromosome complements were analyzed from peripheral blood lymphocytes of a couple who had experinced for spontaneous abortions. The karyotype of the husband was designated as 46,XY, while the wife's karyotype was designated as 46,XX, t(1p;6p). Balanced reciprocal translocations appear to be associated with the recurrent spontaneous abortions experienced by the couple. We report here a case of a maternal (1p;6p) reciprocal translocation in a couple with repeated fetal loss.
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Effect of centchroman on lipid metabolism in genital organs of female rhesus monkeys (macaca mulatta)
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Effect of Centchroman (3,4-trans-2, 2-dimenthyl-3-phenyl-4-p (B-pyrrolidinoethoxy)-phenyl-7-methoxy chroman)treatment at 1 and 2.5 mg/kg; for 3, 6 and 12 months on lipids constituents of uterus,cervix and vagina was studied. Centchroman did not cause any consistent pattern of alteration in lipid contents of uterus, cervix and vagina of female rhesus monkey. However, uterine phospholipids were decreased at both the doses and cervical and vaginal triglycerides increases at higher dose. The altered nature of responses in the genital organs may be due to manifestation of estrogenic-cum-antiestrogenic properties of centchroman.
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Effect of norgestrel and testosterone on male rats
Item Type: Article
Editor:
Year: 00/06/1987
Abstract: Intramuscular administration of Norgestrel, an orally active progestogen, to male rats for 48 days interrupted spermatogenesis and also caused a temporary loss of libido. Testosterone therapy restored libido in progesterone treated rats but not the spermatogenic process. Consequent upon these findings, a new combination of Norgestrel and Testosterone, capable of inducing temporary sterility in male rats, has been evolved.
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Apparent benefit from corticosteroids in bronchopulmonary dysplasia: a case report
Item Type: Article
Editor:
Year: 00/00/1984
Abstract: A case of bronchopulmonary dysplasia complicating the ventilatory management of respiratory distress syndrome is described. The diagnosis was documented by typical clinical radiological and cytopathologic criteria. The infant's abrupt clinical deterioration was reversed by the use of high dosage steroids and attempt at reducing the dose of steroids initially was associated with clinical and radiological deterioration. We conclude that steroid administration seemed beneficial in our patient.
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Age of biological maturity of Malaysian girls by ethnicity
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: This study tries to estimate the age of biological maturity of Malaysian girls by ethnicity by employing an indirect methodology. Age at biological maturity is estimated by considering retrospective fertility and family survey data on marriage, first birth, and contraceptive use. The waiting time for the biological mature females to conceive is 3.0 months; 3.2 months among the Malays, 2.7 months among the Chinese, and 2.8 months among the Indians.The maximum age of attaining biological maturity is 20 for all ethnic groups except Indians (19 years). The expected age biological maturity at birth is 15.6 years; 15.3 years for the Malays, 15.4 for the Chinese and 14.8 years for the Indians.The mean age of attaining biological maturity coincides with the expected age of attaining biological maturity at birth.
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Actinomyces-like organisms in the cervical smears of IUCD users
Item Type: Article
Editor:
Year: 00/01/1983
Abstract: Cervical smears of 128 intrauterine contraceptive device users were stained by Gram stain and screened for the presence of Actinomyces-like organisms. Actinomyces-like organisms were observed in 5.5 percent, pus cell in 20.1 percent and yeast cells in 10.2 percent of the smears examined. The average duration of insertion was 8 months. Smears of 103 controls were negative for Actinomyces-like organisms, pus cells were observed in 8.7 percent and yeasts in 4.8 percent.
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