TOPICS
Results for Topics : "Fertility"
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Dapatan data subfertitli Kebangsaan bagi tahun 2023
Item Type: Infographic
Editor:
Year: 00/12/2024
Abstract: The collection of subfertility data involves all registered hospitals and clinics providing subfertility treatment services throughout Malaysia from January 1, 2023, to December 31, 2023. The collected subfertility data has been approved by NPFDB (LPPKN), including information on the profiles of new female and male clients (husbands) in the current year, as well as details of subfertility treatments carried out at the participating facilities during the same period.
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Exploring environmental contaminants and dietary pattern in relation to infertility in reproductive age women
Item Type: Scientific Poster
Editor:
Year: 00/11/2024
Abstract: Identifying modifiable lifestyle factors, such as diet, that influence human fertility is of major clinical and public health significance. Medical treatment for impaired fecundity is also on the rise. The use of assisted reproductive technologies in Malaysia has steadily increased. This study aims to explore environmental contaminants and dietary pattern in Malaysian reproductive age women. This case control study will involve cross-sectional analysis of 128 women with infertility, with matched 256 regular cycling women from a community-based cohort. Sociodemographic data, mental health, physical activity and dietary intake for 7 days were obtained from interviews using questionnaires. Anthropometric measurements including weight, height, BMI, and body fat percentage were collected. Physical activity data showed that infertile women have lower physical activity compared to those in control and higher stress and depression. Data analysis using multivariate tests showed that an increase in one unit of BMI increased the risk of infertility in women by 1.15 times [Adjusted OR=1.147 (95% CI= 1.059-1.243)])(p<0.01).Meanwhile, high intake of folic acid will reduce the risk of infertility in women by1.0% [Adjusted OR=0.990 (95% CI= 0.981-1.000)] (p<0.05). Likewise, highselenium intake also reduced the risk of infertility in women by 3.0% [Adjusted OR=0.972 (95% CI= 0.949-0.996)] (p<0.05). Significant differences were observed in Anti Mullerian Hormone levels, FSH, LH, lipid peroxidation, advanced glycation end products, inflammatory markers, micronucleus frequency (chromosomal damage), insulin (HOMA-IR), fasting insulin, lipid profile and fasting blood glucose. Based on the hair heavy metal analysis, it was observed that zinc, selenium, calcium and chromium is lower in case group as compared to the control group. On the other hand, lead, copper and cadmium were observed to be higher in case as compared to control. It was observed that urinary bisphenol A and Phtalate metabolites are higher in case group. Di-(2-ethylhexyl) phthalate (DHEP), MEHHP, Mono (2-ethyl-5-hydroxyhexyl) phthalate and MEOHP, mono (2-ethyl-5-oxohexyl) phthalate are detected in our case group. For paraben, only methyl paraben were higher in the cases but not other paraben metabolites. Per- and polyfluorinated substances) concentration observed is not significant. Based on the metabolomic analysis, the pathway with the highest impact factor was the synthesis and degradation of ketone bodies, with an impact factor of 0.60. This indicates that this pathway is very important in the metabolic network and has a significant impact on the overall system. Other pathways with high impact factors include Phenylalanine, tyrosine and tryptophan biosynthesis (0.5), Taurine and hypotaurine metabolism (0.42), Phenylalanine metabolism (0.35), Histidine metabolism (0.32), Cysteine and methionine metabolism (0.274), Glycine, serine and threonine metabolism (0.271), and glyoxylate and dicarboxylate metabolism (0.21). Based on our findings, risk factors which include BMI, intake of folic acid and selenium have a significant relationship with the risk of infertility in women. We have also shown that there is existence of endocrine disrupting chemicals affecting infertility but the cause or the source of contamination is still unknown. Pathway related to ketone bodies and tricarboxylic acid is involved showing the relationship with healthier weight for better reproductive outcome. We have also showed that higher genomic instability and inflammation was observed in those infertile showing that managing dietary and lifestyle related to it is very crucial. Therefore, healthy lifestyle practices need to be improved, targeted and personalized to reduce the risk of infertility in women.
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Meneroka kontaminan persekitaran dan corak diet dalam kalangan wanita umur reproduktif yang mengalami ketidaksuburan
Item Type: Conference or Workshop Item
Editor:
Year: 00/11/2024
Abstract: The environment and dietary patterns have a significant impact on reproductive-age women experiencing infertility. Every year, fertility rates among women decline in many countries. Pollutants are constantly present in our surroundings, and environmental contaminants are commonly found in food, cooking ingredients, medications, and kitchenware that we use daily, which contribute to the causes of female infertility. Therefore, there is a need for monitoring the food industry/chemicals in food and raising public awareness about the importance of being mindful of both their diet and the surrounding environment.
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Project concept: a mixed method study of social psychological influences and affordability perception on fertility intentions in Malaysia
Item Type: Scientific Poster
Editor:
Year: 00/07/2024
Abstract: Malaysia, a culturally rich and economically strong Southeast Asian country, is experiencing a major demographic transition. In 1970, the Total Fertility Rate (TFR) was high at 4.9 children per woman, indicating a preference for larger families. By 2022, TFR has drastically reduced to 1.6 children per woman, below the replacement level of 2.1. Pronounced in urban areas especially Kuala Lumpur, with a TFR or just 1.2. The study aims to bridge gaps in understanding fertility intentions in urban Malaysia. Findings will inform public health policies and family planning programs, contributing to sustainable health systems.
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Peningkatan penyalahgunaan dadah dan masalah kesuburan dalam kalangan belia dan kesan ke atas pertumbuhan penduduk : satu tinjauan awal
Item Type: Scientific Poster
Editor:
Year: 00/07/2024
Abstract: Drug abuse can have an adverse effect on fertility levels and subsequently affect the rate of population growth. The negative effect of drug abuse on the level of fertility is found to be more significant among the youth. More worrying in Malaysia, the youth group (19-39 years) who are in the reproductive age category are also the highest age category detected as drug abusers and addicts (>70% of the total number of addicts) and the percentage of the youth population involved in drugs remains high.
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SDGS and the impact of megatrends on Families: perspectives from Malaysia
Item Type: Conference or Workshop Item
Editor:
Year: 00/05/2024
Abstract: 57th Commissions on Population and Development (CPD57): Assessing the status of implementation of the Programmed of Action of the International Conference on Population and Development and its contribution to the follow-up and review of the 2030 Agenda for Sustainable Development during the decade of action and delivery for sustainable development. Strengthening Malaysian Families in era of megatrends, National Population and Family Development Board Malaysia (NPFBD) had LPPKN Family Centre, Nur Sejahtera Clinic Services, Population and Family Research, Training and education (family), Counseling service and program, online accessibility etc.
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Prosiding Persidangan Kependudukan Kebangsaan 2023 (PERKKS 23): “Penduduk dan Keluarga Mampan, Membangun Malaysia MADANI”
Item Type: Book
Editor:
Year: 00/12/2023
Abstract: Collection of papers presented during the 2023 National Population Conference (PERKKS 23), 21-22 November 2023, Pulse Grande Hotel, Putrajaya.
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Penurunan Kadar Kesuburan Di Malaysia
Item Type: Infographic
Editor:
Year: 00/10/2023
Abstract: Total Fertility rate (TFR) is a demographic indicator used to estimate the average number of children a woman should give birth to during her reproductive period. The findings of a poll in Sarawak found that the total TFR for the state of Sarawak is decreasing drastically. 12.6% of couples have had or are experiencing fertility problems and it is difficult to conceive within a year after marriage.
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Prosiding Persidangan Kependudukan Kebangsaan 2022 (PERKKS 22): “Pemerkasaan Penduduk dan Keluarga, Teras Negara Maju”
Item Type: Book
Editor:
Year: 00/12/2022
Abstract: Collection of papers presented during the 2022 National Population Conference (PERKKS 22), 10-11 November 2022, Bangi Resort Hotel, Selangor.
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